Dr. Rolando F. Del Maestro retired in
2012. His research focuses on the invasiveness of malignant glial cells.
Malignant glial tumours are complex cellular microenvironments containing one
large localized aggregation of tumour cells and smaller subpopulations of
invading tumour cells distant from the main tumour mass. Failure to control
these subpopulations of invading tumour cells may be the key reason for local
and distant recurrence after radical resection and may contribute
substantially to the failure of other modalities of treatment such as
radiotherapy and chemotherapy. The goals of his research are:
1. To characterize the invasive paradigms used by malignant glial cells to
invade three-dimensional matrices using time-lapsed video microscopy
2. To delineate the genetic and biochemical determinants of these invasive
paradigms
3. To develop novel chemotherapeutic approaches to target these invasive
subpopulations of malignant cells
See Publications
E-mail:
Rolando Del Maestro
Web Site: Dr. Del Maestro's
Laboratory
Page last updated: Jan. 11, 2013 at 1:04 PM