Dr. Wayne Sossin is interested in the biochemical changes that occur in the brain during learning and memory. Of particular interest is the identification of molecular memory traces that underlie behavioural memory. Dr. Sossin’s laboratory examine this problem in the simple nervous system of Aplysia where behavioural memory is encoded by changes in the synaptic strength of identified neurons. In this system, we can visualize memory using modern imaging techniques and electrophysiology, and thus investigate the underlying molecular basis of memory. We are investigating several candidates for the molecular trace, including activation of persistent kinases, regulated translation of new proteins and cytoskeletal changes.

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E-mail: Wayne Sossin
Web Site: Sossin lab