The Neuro Team

Dr. Jack Antel, a neurologist, examines how the immune system interacts with cells in the central nervous system. His work deals with immune-mediated neurological diseases, especially multiple sclerosis. Dr. Antel's studies with human tissues are often designed in parallel with the mice models used by his colleague, Dr. Trevor Owens, who studies experimental allergic encephalomyelitis (EAE). Another focus is trying to understand how cells of the immune system injure oligodendrocytes and their myelin membranes. Dr. Antel is also examining how glial cells (astrocytes and microglia) serve as antigen-presenting cells that regulate T-cell reactivity.